Mission Statement

CAM Center Director and  USC, VP for Research

The NIH CAM Center at USC is one of the 11 nation-wide Centers of Excellence funded in October 1, 2007 by National Center for Complementary and Alternative Medicine (NCCAM), an institute of NIH . This Center is now in its second cycle of 5 year, $ 8 million of funding, as of September 1, 2014. The Center is dedicated to understanding the mechanisms by which various plant-derived products can be used as preventive or therapeutic modalities in the treatment of inflammatory and autoimmune diseases. The Center’s current focus is  understanding epigenetic regulation of inflammatory and autoimmune diseases by various plant-derived products.
The long term goals of the Center are to develop bidirectional translational research that will lead to establishment of both bench-to-bedside and bedside-to-bench activities. The past projects of the Center included: 1) To assess the mechanism of actions of resveratrol found in red grape skin on multiple sclerosis, 2) To study the effect of compounds found in hemp seed oil on autoimmune hepatitis and 3) Use of American ginseng on colitis and colon cancer.
The current projects of the Center include: 1) Epigenetic pathways in resveratrol-induced amelioration of neuroinflammation, 2) Epigenetic regulation of Nrf2 signaling pathway in American Ginseng-mediated suppression of inflammation in the colon, 3) Indole-mediated epigenetic regulation of T cells in colitis and 4) Sparstolonin B as a TLR antagonist in suppression of liver inflammation through epigenetic mechanisms
Our Center is supported by state-of-art Analytical Core,  Instrumentation Resource Facility (IRF), and synergistic research interaction between highly talented, experienced and well funded group of investigators with expertise in molecular and cellular immunology, pathology and pharmacology.